Sumalee Kamchonwongpaisan Selected Research

Pyrimethamine (Daraprim)

1/2022	New Insights into Antimalarial Chemopreventive Activity of Antifolates.
1/2022	Structural Insight into Effective Inhibitors' Binding to Toxoplasma gondii Dihydrofolate Reductase Thymidylate Synthase.
12/2018	Hybrid Inhibitors of Malarial Dihydrofolate Reductase with Dual Binding Modes That Can Forestall Resistance.
1/2013	Inducible knockdown of Plasmodium gene expression using the glmS ribozyme.
6/2010	Preclinical evaluation of the antifolate QN254, 5-chloro- N'6'-(2,5-dimethoxy-benzyl)-quinazoline-2,4,6-triamine, as an antimalarial drug candidate.
7/2009	Stepwise acquisition of pyrimethamine resistance in the malaria parasite.
11/2006	Evaluation of the activities of pyrimethamine analogs against Plasmodium vivax and Plasmodium falciparum dihydrofolate reductase-thymidylate synthase using in vitro enzyme inhibition and bacterial complementation assays.

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Sumalee Kamchonwongpaisan Research Topics

Disease

27	Malaria 05/2022 - 06/2006
5	Infections 01/2022 - 09/2011
3	Falciparum Malaria (Plasmodium falciparum Malaria) 12/2018 - 01/2009
2	African Trypanosomiasis (Nagana) 04/2022 - 09/2011
1	COVID-19 04/2022
1	Bites and Stings (Sting) 01/2022
1	Body Weight (Weight, Body) 01/2022
1	Toxoplasmosis 01/2022
1	Diarrhea 11/2020
1	Thalassemia 03/2018
1	Iron Overload 09/2015
1	Cough 12/2013
1	Hypersensitivity (Allergy) 01/2013
1	Parasitemia 04/2012
1	Trypanosomiasis 09/2011
1	Neoplasms (Cancer) 09/2011
1	Fever (Fevers) 08/2010
1	Parasitic Diseases (Parasitic Disease) 03/2009
1	Vivax Malaria 11/2006

Drug/Important Bio-Agent (IBA)

9	Antimalarials (Antimalarial Agents)IBA 01/2022 - 06/2006
8	Pharmaceutical PreparationsIBA 05/2022 - 11/2008
8	Folic Acid AntagonistsIBA 01/2022 - 11/2006
8	Tetrahydrofolate Dehydrogenase (Dihydrofolate Reductase)IBA 01/2022 - 06/2006
7	Pyrimethamine (Daraprim)FDA Link 01/2022 - 11/2006
3	EnzymesIBA 01/2019 - 07/2009
3	Folic Acid (Vitamin M)FDA LinkGeneric 07/2014 - 06/2006
2	Messenger RNA (mRNA)IBA 01/2021 - 10/2007
2	artemisinin (artemisinine)IBA 01/2017 - 10/2015
2	DNA (Deoxyribonucleic Acid)IBA 01/2012 - 11/2008
1	Anti-Infective Agents (Microbicides)IBA 04/2022
1	piperineIBA 04/2022
1	AmidesIBA 04/2022
1	pyrimidineIBA 12/2021
1	PhytochemicalsIBA 11/2020
1	Glucosephosphate Dehydrogenase (Glucose 6 Phosphate Dehydrogenase)IBA 03/2018
1	Hemoglobins (Hemoglobin)IBA 03/2018
1	UbiquitinIBA 01/2017
1	HydrolasesIBA 01/2017
1	Heme (Haem)IBA 11/2016
1	Glutathione (Reduced Glutathione)IBA 01/2016
1	thymidylate synthase-dihydrofolate reductaseIBA 01/2016
1	Catalytic RNA (Ribozymes)IBA 01/2016
1	Isoflurophate (DFP)FDA Link 09/2015
1	Deferoxamine (Desferal)FDA LinkGeneric 09/2015
1	Chelating AgentsIBA 09/2015
1	1- (N- acetyl- 6- aminohexyl)- 3- hydroxy- 2- methylpyridin- 4- oneIBA 09/2015
1	IronIBA 09/2015
1	Deferasirox FDA Link 09/2015
1	TeaIBA 09/2015
1	DeferiproneIBA 09/2015
1	MicronutrientsIBA 09/2015
1	AlkaloidsIBA 12/2013
1	Coloring Agents (Dyes)IBA 04/2012
1	SYBR Green IIBA 04/2012
1	QuinazolinesIBA 06/2010
1	BiguanidesIBA 01/2009
1	Eukaryotic Initiation Factor-4EIBA 10/2007
1	Thymidylate SynthaseIBA 11/2006
1	AsparagineIBA 11/2006
1	Dihydropteroate Synthase (Dihydropteroate Synthetase)IBA 06/2006

Therapy/Procedure

4	Traditional Medicine (Folk Remedies) 12/2013 - 08/2010
2	Therapeutics 11/2020 - 01/2017
1	Chemoprevention 01/2022
1	Art Therapy 10/2015
1	Drug Therapy (Chemotherapy) 09/2011